1373. Using Geospatial Analysis to Describe the Association between Active Tick Surveillance Data and Clinical Cases of Anaplasmosis

Abstract Background Anaplasmosis is a vector-borne disease spread by Ixodes scapularis ticks mainly in the Northeastern United States. The Connecticut Department of Public Health (CT DPH) made anaplasmosis state-wide reportable 2008 and large increase cases was seen between 2014 2019. Methods This study used clinical reported to CT DPH tick infection prevalence data understand emerging geographic hotspots for state evaluate association human infections. Human incidence rates (IR) were calculated per 100,000 population county. Tick as an acarological risk index (ARI) using active surveillance from Agricultural Experiment Station (CAES). These two calculations analyzed with Spearman rank correlation SAS version 9.4 overlaid on ArcMap. Results During 2019-2020 period, 420 included 148 infected identified. There significant positive IR ARI identified (Spearman 0.54, p = 0.03). Litchfield County had highest number (128) Fairfield proportion (11.25%). area greatest both New London (ARI increased 0.073 0.108, 2.64 8.57). Conclusion supports use identifying areas high provides strategy anaplasma infection. Active can be useful guiding public health interventions inform clinician education anaplasmosis. Disclosures All Authors: No disclosures.